CBD otherwise known as Cannabidiol is one of many cannabinoids made inside the cannabis plant.

CBD is a naturally occurring cannabinoid in the hemp plant. It has the ability to bind with cannabinoid receptors in the body and help support the endocannabinoid system.

It’s important to note that CBD is not THC, even though they’re both found in the same plants and have a similar chemical structure. They affect the human body in very different ways, the most notable difference being the fact that CBD has no psychoactive influence, so it’s impossible to ‘get high’ with CBD. This is another factor that makes CBD a viable health supplement.

In most cases, CBD is derived from hemp and not cannabis. The hemp plant contains less than 0.3 percent of THC [5], making it easier to process.

CBD is a naturally occurring cannabinoid in the cannabis plant. It is a 21-carbon terpenophenolic compound that forms as a decarboxylation from the cannabidiolic acid precursor. In more general terms, CBD is a cannabinoid molecule that affects the body’s endocannabinoid system.

The endocannabinoid system plays a vital role in the development of the central nervous system. Moreover, it affects the synaptic plasticity and the response to endogenous and environmental stimuli.[4] CBD molecules, like all cannabinoid molecules, interact with this system. Hence, the endocannabinoid system is comprised of cannabinoid receptors with which CBD tends to bind.

However, CBD is not THC. Even though both of them have a similar chemical structure and are found in the same plants, they have a very different effect on the human body. The most notable difference lies in the psychoactive influence. It is impossible to “get high” with CBD.

Because of its balancing health properties and lack of psychoactive effects, CBD is used for a wide variety of health benefits. Moreover, in most cases, CBD comes from hemp. The hemp plant contains less than 0.3 percent of THC.[5]

CBD tincture is easy to administer and one of the simplest ways to experience the benefits of CBD.

To understand CBD, it’s important to know about the existence and purpose of the body’s endocannabinoid system or ECS. The ECS is an organ system whose main function is to bring balance to other organ systems including the digestive, endocrine and immune system - pretty much boosting all-around wellness. The ECS has cannabinoid receptors all over the body, which interact with compounds called cannabinoids to support its healthy functioning.

The body produces its own cannabinoids (called endocannabinoids), but with today’s modern life, diet and the stresses we put on our minds, we use them up quickly and the ECS benefits from extra support.

That’s where CBD comes in.

CBD tincture effects can vary from mild, advanced to therapeutic. Furthermore, the results also depend on the dosage, administration method and the frequency with which you’re using the product.

For the most optimal results, it’s advisable to use CBD at least twice a day - it would take at least a week before you notice the difference.

Ingestion

The most common way to administer CBD is through oral ingestion. With oral intake , the options range from : edibles, capsules, drops, drinks and more. However, most beginners tend to use tinctures or drops because they are very easy to use and have the most versatility.

When you take CBD orally, it passes to the digestive system, and is then metabolized by the liver. Once that process is over, it enters your bloodstream, and the active compounds start affecting the endocannabinoid system. This is how the human body processes most orally ingested vitamins and supplements.

You can even put CBD in beverages like coffee or smoothies.

Sublingual

Sublingual administration of CBD oil tinctures or drops is an efficient way to absorb CBD via the mucous membranes in your mouth

Sublingual CBD directions: place the desired number of drops of CBD under your tongue and hold it for up to 90 seconds. This gives the mucous membranes in the mouth enough time to absorb the oil.

This method is more effective than normal ingestion because sublingual application bypasses the digestive system and liver, so the active compounds of the CBD oil can get to your bloodstream sooner. If faster relief sounds like something you’d like, this might be the option for you.

Topical

Topical CBD products like balms and salves, have a direct effect on the area being treated and don’t have to first enter the bloodstream.The CBD is absorbed by the skin and interacts with cannabinoid receptors in nearby cells. These can be used for localized relief from aching joints, soreness or inflammation as well as daily skin health care.

A tincture is a specific categorization of CBD product, much like edibles or topicals.

CBD tinctures are made from high CBD strains of hemp, and are primarily used to help relieve anxiety or ease pain. Tinctures can be taken orally or sublingually (under the tongue).

CBD tinctures are liquid solutions that are designed to host the benefits of CBD oil combined with additional elements. Tinctures are convenient, have a long shelf life, and are absorbed easily when taken under the tongue. The dose can be adjusted easily by increasing or decreasing the number of drops taken, making it an ideal formulation for those new to taking CBD.

CBD tincture should be administered in small doses because it is a concentrated solution. The best way To take CBD tincture, especially for therapeutic purposes, is to put the drops under your tongue. That’s the reason why almost all tinctures come with a built-in dropper that allows users to take carefully measured quantities.

According to recent research[7] on CBD administration methods, sublingual use makes CBD more efficient and consistent in the body than other oral alternatives.

However, there is more than one way to take CBD tinctures.

Other than the sublingual method, you can also put the drops in food. Depending on your preferences you can mix the CBD drops with your morning coffee, smoothie, water, soup and pasta. The effect of the drops doesn’t change if you use them with food. However, it may take longer for you to feel the effects since the CBD has to be processed by your digestive system and liver first. Oral ingestion also reduces bioavailability to an extent, since some of it will be lost in the digestive process.

When the drops are administered with food, the active substances have to go through the digestive system and the liver before they reach the bloodstream.

Item descriptionAs of the writing of this extensive guide, there is not a known case of CBD overdose or a toxicity case. According to a recent study[9] on the safety and possible side effects of CBD use, it was established that:

“…CBD does not induce changes on food intake, does not induce catalepsy, does not affect physiological parameters (heart rate, blood pressure and body temperature), does not affect gastrointestinal transit and does not alter psychomotor or psychological functions.”[10]

CBD could potentially interfere with levels of certain blood thinners. Similar to grapefruit juice, it can also interact with other medications.[8] If you’re unsure whether CBD interacts with your medications, feel free to consult with your doctor before taking it.

The quality of the CBD you take is also heavily reliant on the quality of the hemp. If the hemp was grown in a toxic environment (poisonous pesticides or in soil containing heavy metals), then the product is going to carry the same chemicals. This is by far the biggest risk factor when it comes to CBD products.[11]

Note: Make sure your CBD tincture is third party lab tested.

There is no ideal CBD dosage for everyone. Because of numerous variables like weight, diet, metabolism, genetics, environment, product consistency and others, it’s not possible to determine one dosage that would fit everyone equally.[12]

The FDA has not created a Recommended Daily Intake (RDI) for CBD, which means CBD does not have an official serving size. However, CBD Oil Review (COR) have created an official COR Serving Standard through extensive analysis of hundreds of CBD products. Their general guidelines are 25 mg of CBD, taken twice a day.[14]

With this in mind we at Hemisphere Farms created our lower dose 750 mg tincture so that each dropper full contains exactly 25 mg of CBD. For those requiring higher doses we offer the 1500 mg formulation, delivering 50 mg per dropper.

A Full-spectrum CBD tincture contains not only CBD, but other compounds from the hemp plant too such as terpenes, flavanoids and phytocannabinoids. This has been found to increase the bioavailability and efficacy of the solution , providing maximum support and balance to one’s overall well-being.

Our Hemisphere Farms tincture is a full-spectrum CBD containing a balance of several compounds in the hemp plant. These compounds work in synergy with each other to increase efficacy and use in the body. This is commonly referred to as the ‘entourage effect’ in supplements.

Moreover, when you use a full-spectrum CBD, you’re also gaining the individual benefits from the other cannabinoids found in the plant in addition to the benefits of their synergy.

While CBD is the main ingredient, some of the other cannabinoids that have beneficial influence are:

THCV – promotes bone health

CBCA and CBC – support the reduction of inflammation and fungal infection

CBGA and CBG – support the reduction of bacterial growth[15]

The enhanced efficiency of full-spectrum CBD was proven by a research study[16] where full-spectrum CBD and CBD isolate were administered to two different groups of mice. The group that was given full-spectrum CBD showed higher absorption rates and bioavailability.

CBD provides a natural, organic path to anxiety relief. For those looking for a more natural, non-pharmacological approaches, CBD has proved to be quite popular. Researchers believe that CBD’s effects on anxiety may be due to its ability to regulate serotonin production through the endocannabinoid system. According to a study published in [Neuropsychopharmacology][2] CBD may aid and lessen social anxiety. The research was conducted with a sample of 24 participants that experienced regular anxiety.

https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf
http://haleighshope.co/blog/17-compelling-studies-cbd-2017/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789136/
https://ministryofhemp.com/hemp/not-marijuana/
https://medium.com/cbd-origin/what-is-cbd-bioavailability-and-why-does-it-matter-69d9a2e37e6c
https://www.alchimiaweb.com/blogfr/wp-content/uploads/2016/07/Current-Status-and-Prospects-for-Cannabidiol-Preparations.pdf
https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
https://www.ncbi.nlm.nih.gov/pubmed/22129319
https://www.ncbi.nlm.nih.gov/pubmed/22129319
https://keytocannabis.com/blogs/cannabis/is-cbd-oil-safe-yes-benefits-outweigh-risks
https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/
https://www.projectcbd.org/guidance/cbd-users-manual
https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/
https://medium.com/cbd-origin/cbd-isolate-vs-full-spectrum-cbd-b78a6eab319c
http://file.scirp.org/pdf/PP_2015021016351567.pdf
https://www.projectcbd.org/managing-nausea-cannabis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938896/
https://www.healthline.com/nutrition/cbd-oil-benefits#section4
https://www.ncbi.nlm.nih.gov/pubmed/25061872
https://www.verywellhealth.com/cbd-oil-for-anxiety-4176279
https://www.nature.com/articles/npp20116
https://www.projectcbd.org/about/ask-project-cbd/vaporization-cbd-thc-boiling-points
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686045/

Frequently Asked Questions

What is Cannabinoid?